The following article is outdated. You can view the updated guide here.
DiskAid like iTunes works through mobile devices backups - which could be pretty large files, in the end.
Some Mac OS X users might want to relocate the MobileSync folder to gain precious operating disk space and move this folder to an alternate or external location.
DiskAid will work just fine with this, as long as the correct procedure - which is described in this article.